By Johannes Ring
This booklet provides the cutting-edge in study into atopic dermatitis, or atopic eczema, and gives quite a few powerful sensible administration ideas which are grounded within the colossal medical adventure of the writer. a systematic evidence-based method of the topic is followed, progressing from scientific signs in numerous illness phases, molecular genetics, and pathophysiology via to remedy and prevention. All facets of sufferer administration are coated, together with diagnostics, avoidance concepts, emollient remedy, and acute remedy of eczema and itch. diversified targeted healing methods are mentioned, starting from glucocorticoids, topical calcineurin inhibitors, and antimicrobial treatment via to UV treatment, allergen-specific immunotherapy, systemic immunosuppressive remedy, and rising concepts. Environmental affects are thought of, and there's a concentrate on the complete individual, with cognizance to psychosocial facets of the illness and the good thing about academic courses reminiscent of “eczema schools”. Atopic Dermatitis may be worthy for dermatologists, allergists, pediatricians, and common practitioners and informative for different folks and sufferers.
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Additional info for Atopic Dermatitis: Eczema
It is important to stress that there are these manifestations since they are not clearly mentioned in many textbooks. lichenification, prurigo-type excoriated papules, etc. , Staphylococcus aureus (see Sect. 6). This morphology also can be observed in circumscribed skin lesions with nummular variants (see Page 37). Whether nummular eczema in childhood represents an own identity is still to be discussed. In the opinion of the author, this nummular variant is a subtype of atopic eczema in childhood.
8 In 1980, Vickers published a prospective study on 2000 children from the pediatric dermatology department in Leeds with a follow-up of up to 21 years: in around 90 % of the children, eczema disappeared, and they stayed in remission when they had reached the age of ten (Vickers 1980). However, there were critical comments to this study, since it was only one observer who designed the study and examined the children, and also the definition of “remission” was not clear. Furthermore—and this is the most crucial critical issue—he also included “eczema infantum” which at first might have been seborrheic dermatitis (see above).
High IgE levels in serum, concomitant existence of atopic respiratory disease, as well as strong psychosomatic involvement seem to be risk factors for a longer persistence of eczema. 6 14 20 Time (Years) Development of asthma: the more severe the atopic eczema in infants, the higher the risk of asthma development in childhood. In a study by Gustafsson et al. with 94 children with atopic eczema, 30 % of children with mild eczema developed asthma and 25 % allergic rhinitis, while children with severe atopic eczema developed asthma after 8 years in 70 % and hay fever in 90 % (see Ring et al.
Atopic Dermatitis: Eczema by Johannes Ring